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Summary: After starting rivaroxaban for treatment of cancer-associated deep vein thrombosis (DVT) with pulmonary embolism (PE), a 69-year-old Caucasian woman arrived at an oncology clinic with a diffuse, exanthematous (morbilliform) rash on her neck . To our knowledge, there is only one other reported case due to apixaban in the literature [ 1 ]. (2015). You should always consult your doctor or another healthcare professional before taking any medication. If you have constipation or diarrhea with Eliquis, talk with your doctor. But stopping Eliquis treatment suddenly can increase your risk of blood clots. Only valid in the United States, Puerto Rico, and other select U.S. 2005-2023 Healthline Media a Red Ventures Company. Females who are able to become pregnant: talk with your healthcare provider about pregnancy planning, and your risk of severe uterine bleeding if you are treated with blood thinner medicines, including ELIQUIS. Do not run out of ELIQUIS. Eliquis has a boxed warning for the increased risk of blood clots if treatment is stopped early. Try wearing loose clothing and reducing skin-to-skin friction in affected areas. For example, if the rash is very itchy, an antihistamine or oral steroid can help manage the itching until the rash clears up. Last medically reviewed on August 29, 2022, Blood clots can form in many different parts of the body. Cellulitis Symptoms. If used during pregnancy, Eliquis may increase the risk of bleeding during pregnancy and delivery. Rashes in Eliquis; How the study uses the data? Warfarin is an anticoagulant medicine (blood thinner). They can then use this information to adjust your treatment plan if needed. Allergic reaction. Learn more here. You should avoid drinking large amounts of alcohol while taking Eliquis. All other trademarks are property of their respective companies. Examples include: If your doctor confirms youve had a mild allergic reaction to Eliquis, theyll decide if you should continue using it. No, its not known to. Eliquis can cause certain side effects, some of which are more common than others. It's important to keep the area clean and dry. Bruising was a common side effect reported by people in studies of Eliquis. Because Eliquis is used to prevent blood clots from forming, it is commonly referred to as a blood thinner. This is not a complete list of possible side effects. Eliquis reduces your bloods ability to form clots, and as a result, it can increase your risk of bleeding. If you notice blood in your urine, or you have pink or red urine while taking Eliquis, see your doctor right away or call 911 or your local emergency number. Because its not known if breastfeeding while taking Eliquis is safe, its currently not recommended. Its a prescription drug used in adults to prevent or treat blood clots in certain situations. Before you start taking this drug, tell your doctor about any bleeding disorder you have. A reaction to ELIQUIS can cause hives, rash, itching, and possibly trouble breathing. Get answers to some frequently asked questions about the side effects of Eliquis. All decisions regarding patient care mustbe made with a healthcare provider, considering the unique characteristics of the patient. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. They may recommend scheduling your procedure when youll have the least amount of Eliquis in your body. There are many medications used to treat atrial fibrillation (AFib). For more information, see the Side effects explained section above. None of it's unbearable (yet). AFib Not Caused by a Heart Valve Problem. They include: Hemorrhage: Serious bleeding in the gastrointestinal tract Serious bleeding in the brain (hemorrhagic stroke) Serious bleeding within the eye Anemia Nausea * This clot may press on your spinal cord, which could cause long lasting or permanent paralysis. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Learn more. If you suspect you have a drug rash, talk with your doctor right away. Before taking apixaban, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Territory. Talk with your doctor if youre concerned about kidney-related side effects with Eliquis. anemia (low red blood cell count) thrombocytopenia (low platelet count) low blood pressure, which may cause . For more information about Eliquis, including details about its uses, see this in-depth article. You can stop taking Eliquis without tapering your dosage first. A drug rash or other reaction may occur for several reasons, such as: In some cases, drug rashes can be idiopathic, meaning theres no known direct cause. If you develop serious side effects while taking Eliquis, call your doctor right away. In clinical trials, some people taking Eliquis reported having blood in their urine, which could be a sign of bleeding in the kidneys. The risk of bleeding may be higher if you have a deformed spine, or have had spinal procedures/surgery before (such as epidural catheter placement, difficult epidural/spinal puncture), or are taking other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, "blood thinners" such as warfarin/enoxaparin, nonsteroidal anti-inflammatory drugs-NSAIDs such as ibuprofen). To the pharmacist: For processing assistance, please call McKesson Pharmacy Support at 1-866-279-4730. However, some of these rashes may be accompanied by itching or tenderness. Find out how to know if you have one and what to do about it. And some may be easily managed. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). Refill your prescription before you run out. You should also call your doctor right away if you fall and hit your head or have any other kind of head injury. Ask your doctor what other medications may be better options for you. If you get this reaction, it will usually happen soon after you take a dose of ELIQUIS. Mild reactions usually clear up once you stop taking the drug. If you have a blood disorder called triple-positive APS, you may have a raised risk of blood clots with Eliquis. Applying an ice pack can also help to stop minor bleeding. Boxed warnings are the most serious warnings from the Food and Drug Administration (FDA). This site is intended for U.S. residents 18 years of age or older. Talk with your doctor about your health history before starting Eliquis. Your doctor will recommend treating the bleeding before you start treatment with Eliquis. ELIQUIS can cause bleeding, which can be serious, and rarely may lead to death. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. This fluid can be tested to help your doctor diagnose certain conditions. Treatment and home management for blood clots, How to tell if it is a bruise or a blood clot, Blood-thinning foods, drinks, and supplements, help prevent DVT and PE from occurring again after the initial clot has been treated, help prevent DVT and PE after hip or knee replacement surgery, Spinal blood clots with spinal procedures., Increased risk of blood clots if Eliquis treatment is stopped early., have had past spinal surgery or problems with your spine, have had difficult or repeated spinal procedures in the past, have an epidural catheter (thin tube placed into your spine to deliver medication), bleeding that takes longer than usual to stop, menstrual periods that are heavier than usual or last longer than usual, avoiding contact sports and other sports with a risk of injury, wearing gloves when using tools such as knives or scissors, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your mouth, tongue, or throat, which can make it hard to breathe. There are many things people can eat and drink that may help keep the blood thin and reduce the chances of developing dangerous clots. Symptoms can be mild or serious and can include: For mild symptoms of an allergic reaction, call your doctor right away. For more information, see the Side effect specifics section above. Discover 6 frequently asked questions about blood thinners and alcohol, answered by an expert. For People at Risk of Stroke due to AFib Not Caused by a Heart Valve Problem. Our website services, content, and products are for informational purposes only. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. certain antibiotics, including tetracycline, SJS involves less than 10 percent of your body, a buildup of the drug that causes toxicity to the skin, a drug makes the skin more sensitive to sunlight, a viral infection and taking an antibiotic, a weakened immune system due to an underlying condition or other drug. You should not stop taking Eliquis unless youre advised to by your doctor. SJS and TEN are considered the same condition, but theres a slight difference between the two: Both SJS and TEN are marked by large, painful blisters. ELIQUIS is available in 2.5-mg and 5-mg tablets. You are about to leave the Bristol Myers Squibb and Pfizer ELIQUIS.com site. You may have a higher risk of bleeding if you take blood thinners and take other medicines that increase your risk of bleeding. In studies, the majority of people taking Eliquis were ages 65 years and older. Can poor sleep impact your weight loss goals? To learn more, you can refer to Eliquiss prescribing information. ELIQUIS may need to be stopped prior to surgery or a medical or dental procedure. As with many medications, higher dosages of Eliquis are more likely to cause side effects than lower dosages. If youre concerned about side effects that you may have while taking a higher dosage of Eliquis, talk with your doctor or pharmacist. A lumbar puncture is a procedure where fluid is collected from your spinal cord. The Best 8 Home Remedies for Cysts: Do They Work? Get medical help right away if you have any signs of very serious bleeding, including: vision changes, confusion, trouble speaking, weakness on one side of the body. No, older people do not seem to have a higher risk of side effects from Eliquis than younger people. Read on to learn about potential common, mild, and serious side effects. This site is intended for U.S. residents 18 years of age or older. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. But if you have any symptoms that are ongoing or bother you, talk with your doctor or pharmacist. They alert doctors and patients about drug effects that may be dangerous. For more information on this boxed warning, see the Side effects explained section below. If you get this reaction, it will usually happen soon after you take a dose of ELIQUIS. Use an electric razor when shaving and a soft toothbrush when brushing your teeth. We avoid using tertiary references. Eliquis works to prevent blood clots from occurring or to treat a blood clot that you already have. unexpected bleeding or bleeding that lasts a long time, such as unusual bleeding from the gums, nosebleeds that happen often, or menstrual or vaginal bleeding that is heavier than normal, bleeding that is severe or you cannot control, red, pink, or brown urine; red or black stools (looks like tar), coughing up or vomiting blood or vomit that looks like coffee grounds. If you miss a dose, take it as soon as you remember. Examples of commonly reported side effects of Eliquis. You can then share this information with your doctor. These include severe urticaria, erythroderma, SJS/TEN, anticoagulant-induced skin necrosis, and DRESS. However, if you stop Eliquis sooner than your doctor recommends, you may have an increased risk of blood clots. Stopping ELIQUIS increases your risk of having a stroke. ELIQUIS is a prescription medicine used to treat blood clots in the veins of your legs (deep vein thrombosis) or lungs (pulmonary embolism), and reduce the risk of them occurring again. A head injury could cause bleeding inside your skull or in your brain while youre taking Eliquis. You are insured by commercial insurance and your prescription insurance coverage does not cover the full cost of your prescription, that is,you have a, You do not have prescription insurance coverage through a state or federal healthcare program, including but not limited to Medicare Part D, Medicaid, Medigap, Veterans Affairs (VA), or Department of Defense (DOD).